Multisystem Inflammatory Syndrome in Children (MIS-C) is a rare but serious condition associated with COVID-19. MIS-C can cause inflammation of multiple organs including the heart, lungs, liver, kidneys, skin, eyes, and digestive system. Although the exact cause of MIS-C is unknown, many children with MIS-C have had a recent COVID-19 infection or had been in contact with someone with COVID-19.
Typically, symptoms of MIS-C present two to six weeks after an acute infection or exposure. However, rare cases of MIS-C occurring 2-3 months after infection or exposure have been reported. Symptoms of MIS-C generally start mildly and may include persistent fever, abdominal pain, vomiting, diarrhea, skin rash, headache, and muscle pain. In rare instances, these symptoms may become worse and require immediate care.
Please note that MIS-C is a reportable condition to DHEC (urgently reportable by phone within 24 hours to the regional health department).
Information for Health Care Providers
Multisystem Inflammatory Syndrome in Children (MIS-C)
DHEC Health Advisory
Information for Parents
CDC: Multisystem Inflammatory Syndrome in Children (MIS-C)
Reported Cases of Multisystem Inflammatory Syndrome in Children (MIS-C) in South Carolina
