COVID-19 Vaccine Provider Guidance

Kids 6 months and older



COVID-19 Education & Outreach Materials

DHEC provides flyers, posters, fact sheets, handouts, PSAs, social media graphics and more that help share factual, important information in English and Spanish about COVID-19 and the COVID-19 vaccines. Access our Education & Outreach materials here.

COVID-19 Vaccine Provider Updates

COVID-19 Grand Rounds for Clinicians and Vaccine Providers

The Infectious Diseases Division of Prisma Health Medical Group in collaboration with the South Carolina Medical Association, South Carolina Hospital Association, University of South Carolina, and DHEC provides a weekly COVID-19 Virtual Grand Rounds Series. This educational activity is free of charge and offers Continuing Education credits (CEU) for physicians, nurses, and pharmacists. (CEU credit is available only for those joining presentations live, not for viewing archived recordings.) This series addresses a variety of topics around SARS-Co-V-2 and COVID-19 disease. Presenters include DHEC leadership, clinicians, and Health Care Administrators.

To join these sessions live (Tuesdays 12-1 p.m.) visit, create a free account, and view calendar for upcoming presentations. You need to register for each presentation. To view previously recorded sessions, visit and in the "Series" drop-down menu select "COVID-19 Virtual Grand Rounds."

Guidance for COVID-19 Allocation

COVID-19 Vaccination Provider Enrollment

To receive and administer COVID-19 vaccine and supplies, providers have to enroll in a federal vaccine distribution program, coordinated through the state's immunization program (unless they are part of a national chain that registered directly with the CDC). The federal government will procure and distribute the vaccine at no cost to enrolled providers. 


Frequently Asked Questions (FAQs) for Vaccination Providers Enrollment

We will continue to update this information to provide the most factual and current information. Click here to view frequently asked questions.

Frequently Asked Questions (FAQs) for Vaccination Reimbursement

We will continue to update this information to provide the most factual and current information. Click here to view frequently asked questions.

SIMON for Vaccine Providers

South Carolina's Statewide Immunization Online Network (SIMON) launched September 13, 2020, as a new immunization information system that will help the agency and immunization providers ensure access and availability of essential immunizations to help keep South Carolinians healthy. Access SIMON

Inventory Reporting Requirement for Enrolled COVID-19 Providers

The COVID-19 Vaccination Program Provider Agreement requires providers to report vaccine supply information as directed by CDC. Locations receiving COVID-19 vaccine should report supply information to VaccineFinder using the online COVID Locating Health Provider Portal. Vaccination providers can report manually via the secure COVID Locating Health Provider Portal, or via an automated secure data transfer directly to the COVID Locating Health Platform. Questions? Please email

Additional helpful resources and information:

Vaccine Administration Management Systems (VAMS)

VAMS is a secure, web-based tool built to help DHEC, vaccination clinics, organizations/employers, and vaccine recipients manage COVID-19 vaccination efforts. It supports operations and data collection and tracking to meet CDC, Operation Warp Speed (OWS), and South Carolina DHEC COVID-19 vaccination requirements. Activated providers will receive detailed instructions related to VAMS Onboarding in their activation notification email.


VAMS Readiness Checklists

Standard & Mobile Clinics

Third Party Clinics

Inventory Manager

Organization Coordinator


Questions? Please email

COVID-19 Vaccine Provider Training and Information Resources

CDC has developed a robust resource portfolio of COVID-19 vaccination resources for vaccine providers. Follow this link to view resources on patient education materials, COVID-19 vaccine training modules, and COVID-19 vaccine storage and handling.

Reporting Temperature Excursions COVID-19 Vaccines


View Archived Vaccine Provider Webinars


COVID-19 Provider Updates COVID-19 Vaccine Provider Statewide